Alzheimer’s disease: Insulin a new causative

The annual mortality rate of Alzheimer’s in Sri Lanka is 20.1 per 100,000 people, resulting in a decrease in quality of life due to the 303.9 annual years of healthy life lost per 100,000 people. According to statistical analysis, Alzheimer’s and dementia in Sri Lanka has increased since 1990 by 87.9% an average of 3.8% a year.

As the incidence of Alzheimer’s is on the rise, conceivably it may be time to rethink the causative factors of Alzheimer’s. According to latest research, it has come to light that insulin, type II diabetes, have an impact on brain function. The decline in insulin growth factor has generated neural vulnerability to stress followed by the inability of the brain to repair damage over time.

This hypothesis was proven by a study carried out in in vivo studies using brain tissues obtained from Alzheimer’s patients. It proved that apart from diabetic patients, non-diabetic patient also exhibited the loss of insulin as a growth factor.

This in turn directs towards the utilization of diabetic drugs to treat Alzheimer’s patients. Studies carried out on animal models have shown impressive results followed by the initiation of several clinical trials down this avenue.
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