Colorectal cancer: Treatment set for clinical
In Sri Lanka, colorectal cancer is on the rise affecting approximately those over the age of 50 years. According to a study carried out by Prof. Kemal Deen and team, it indicated that the current national crude annual incidence is 3.2 per 100,000 in women and 4.9 in men. The average age of disease presentation of such cancer was 60 years in both men and women followed by >28% of the patient to be less than 50 years of age.
However, a new study published in the journal of Cancer Immunology and Research led by researchers at Thomas Jefferson University in Philadelphia, stated that an immunotherapy know as chimeric antigen receptor (CAR) T-cell therapy proved positive when tested on animal models indicating the termination of the tumors, thus, preventing metastasis. The successful completion of the preclinical stage bring about phase I clinical trials in human patients.